Linear least-squares method for unbiased estimation ofT1from SPGR signals

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Linear least-squares method for unbiased estimation of T1 from SPGR signals.

The longitudinal relaxation time, T(1), can be estimated from two or more spoiled gradient recalled echo images (SPGR) acquired with different flip angles and/or repetition times (TRs). The function relating signal intensity to flip angle and TR is nonlinear; however, a linear form proposed 30 years ago is currently widely used. Here we show that this linear method provides T(1) estimates that ...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2008

ISSN: 0740-3194,1522-2594

DOI: 10.1002/mrm.21669